Targeted therapy in inflammatory breast cancer
نویسندگان
چکیده
منابع مشابه
Targeted Therapy in Breast Cancer.
Currently targeted drug selection in breast cancer is exclusively based on estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor (HER2) expression mainly of the primary tumor, even if metastatic disease is actually treated. Retrospective data indicate discordance regarding those factors between primary tumors and corresponding metastatic lesions in up to...
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improve the efficacy of antihormonal therapy and may overcome endocrine treatment resistance at least temporarily in many patients. However, the impressive array of possible treatment combinations and sequences warrants an enormous amount of further research to identify optimal treatment algorithms. Further research will also have to focus on the exploration and establishment of predictive fact...
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Breast cancer is the most commonly diagnosed malignancy and one of the major causes of death among women. Breast cancer is also one of the most investigated diseases but whose biological features are still not well understood, several effective treating strategies having been explored in dealing with different types of advanced breast cancer, such as endocrine therapy and molecular targeted the...
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Personalized and targeted treatments are the most discussed topics in oncology. However, how much personalized medicine is standard of care nowadays and how much is part of our hope for a better future? So far, only a few targeted therapies are available in daily practice for the treatment of human epidermal growth factor receptor 2 (HER2)-negative breast cancer. And even for these few targeted...
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ژورنال
عنوان ژورنال: Cancer
سال: 2010
ISSN: 0008-543X
DOI: 10.1002/cncr.25171